How To Make clean Your Arteries With One Simple Fruit

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The future of cardiovascular disease prevention and handling will non be found in your medicine chiffonier, rather in your kitchen cupboard or in your back chiliad growing on a tree.

Pomegranate Found To Prevent Coronary Artery Disease Progression

A new study published in the journal Atherosclerosis confirms that pomegranate excerpt may preclude and/or reverse the primary pathology associated with cardiac mortality: the progressive thickening of the coronary arteries acquired past the aggregating of fat materials known every bit atherosclerosis.[i]

Mice with a genetic susceptibility towards spontaneous coronary artery blockages were given pomegranate extract via their drinking h2o for ii weeks, kickoff at 3 weeks of age.

Despite the fact that pomegranate treatment actually increased cholesterol levels associated with very low density lipoprotein-sized particles, the handling both reduced the size of the atherosclerotic plaques in the aortic sinus (the dilated opening in a higher place the aortic valve) and reduced the proportion of coronary arteries with occlusive atherosclerotic plaques.

Remarkably, the researchers too plant that pomegranate extract treatment resulted in the following beneficial effects:

Reduced levels of oxidative stress
Reduced monocytie chemotactic protein-1, a chemical messenger (chemokine) associated with inflammatory processes inside the arteries.
Reduced lipid accumulation in the centre muscle
Reduced macrophage infiltration in the heart musculus
Reduced levels of monocyte chemotactic poly peptide-one and fibrosis in the myocardium
Reduced cardiac enlargement
Reduced ECG abnormalities

How can something as benign and commonplace as a fruit extract contrary so many aspects of coronary artery disease, simultaneously, as evidenced by the study above?

The respond may lie in the fact that our ancestors co-evolved with certain foods (fruits in particular) for then long that a lack of adequate quantities of these foods may directly issue in deteriorating organ function.

Indeed, 2-time Nobel Prize winner Linus Pauling argued that vitamin C deficiency is a key cause of cardiovascular disease, owing to the fact that our hominid primate ancestors once had yr-round access to fruits, and every bit a upshot lost the power to synthesize it. [see Linus Paulingvitamin C lecture on GreenMedTV]

This study adds to the already extant torso of clinical research indicating that pomegranate can help unclog your arteries.

For instance, back in 2004, the journal Clinical Diet published the results of a three twelvemonth clinical trial in an Israeli population, finding that the daily consumption of pomegranate juice reversed carotid artery stenosis by up to 29% within 1 year.

Remarkably, the blockages in the control group increased ix%, indicating that pomegranate's artery unblocking effects were even greater than at first apparent. [ii]

Pomegranate'due south value in cardiovascular affliction is quite broad, as evidenced by the following experimentally confirmed backdrop:

Anti-inflammatory: Like many chronic degenerative diseases, inflammation plays a significant office in cardiovascular illness pathogenesis. There are v studies on GreenMedInfo.com indicating pomegranate's anti-inflammatory properties.[iii]
Blood-Pressure Lowering: Pomegranate juice has natural angiotensin converting enzyme inhibiting properties, [iv] and is a nitric oxide enhancer, two well-known pathways for reducing blood pressure.[5] Finally, pomegranate excerpt rich in punicalagin has been plant reduce the adverse effects of perturbed stress on arterial segments exposed to disturbed flow.[vi]
Anti-Infective: Plaque buildup in the arteries often involves secondary viral and bacterial infection, including hepatitis C and Chlamydia pneumoniae.[vii] Pomegranate has a broad range of anti-bacterial and anti-viral backdrop.
Antioxidant: One of the means in which claret lipids become heart disease-promoting (atherogenic) is through oxidation. LDL, for instance, may be technically 'elevated' merely harmless every bit long equally information technology does not readily oxidize. Pomegranate has been found to reduce the oxidative stress in the claret, as measured by serum paraoxonase levels. 1 study in mice found this decrease in oxidative stress was associated with 44% reduction in the size of atherosclerotic lesions. [8]

Resource:

[i] Aishah Al-Jarallah, Fatima Igdoura, Yi Zhang, Christine B Tenedero, Elizabeth J White, Melissa Eastward Macdonald, Suleiman A Igdoura, Bernardo Fifty Trigatti. The effect of pomegranate extract on coronary avenue atherosclerosis in SR-BI/APOE double knockout mice. Atherosclerosis. 2022 May ;228(1):eighty-9. Epub 2022 Mar 7. PMID: 23528829
[2] Michael Aviram, Mira Rosenblat, Diana Gaitini, Samy Nitecki, Aaron Hoffman, Leslie Dornfeld, Nina Volkova, Dita Presser, Judith Attias, Harley Liker, Tony Hayek. Pomegranate juice consumption for iii years past patients with carotid artery stenosis reduces common carotid intima-media thickness, claret pressure level and LDL oxidation. Clin Nutr. 2004 Jun;23(3):423-33. PMID: 15158307
[iii] GreenMedInfo.com, Pomegranate's Anti-Inflammatory Properties
[iv] Mahalaxmi Mohan, Harshal Waghulde, Sanjay Kasture. Outcome of pomegranate juice on Angiotensin II-induced hypertension in diabetic Wistar rats. Phytother Res. 2009 Dec 17. PMID: 20020514
[five] Filomena de Nigris, Maria Luisa Balestrieri, Sharon Williams-Ignarro, Francesco P D'Armiento, Carmela Fiorito, Louis J Ignarro, Claudio Napoli. The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats. Nitric Oxide. 2007 Aug ;17(i):50-iv. Epub 2007 May 5. PMID: 17553710
[half-dozen] Filomena de Nigris, Sharon Williams-Ignarro, Vincenzo Sica, Lilach O Lerman, Francesco P D'Armiento, Russell East Byrns, Amelia Casamassimi, Daniela Carpentiero, Concetta Schiano, Daigo Sumi, Carmela Fiorito, Louis J Ignarro, Claudio Napoli. Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis. Cardiovasc Res. 2007 January 15;73(2):414-23. Epub 2006 Sep 1. PMID: 17014835
[vii] Yasunori Sawayama, Kyoko Okada, Shinji Maeda, Hachiro Ohnishi, Norihiro Furusyo, Jun Hayashi. Both hepatitis C virus and Chlamydia pneumoniae infection are related to the progression of carotid atherosclerosis in patients undergoing lipid lowering therapy. Fukuoka Igaku Zasshi. 2006 Aug;97(8):245-55. PMID: 17087362
[eight] M Aviram, L Dornfeld, Chiliad Rosenblat, Due north Volkova, M Kaplan, R Coleman, T Hayek, D Presser, B Fuhrman. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet assemblage: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr. 2000 May ;71(5):1062-76. PMID: 10799367